This is the problem many of us have been concerned about – immune escape from new SARS-CoV-2 variants in addition to their increased transmission.
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January 18, 2021 at 11:52 PM - Views: 89 #396015leftcoast mountainsParticipant
- Total Posts: 5,523
This is the problem many of us have been concerned about – immune escape from new SARS-CoV-2 variants in addition to their increased transmission. In this case, in a quick (single?) evolutionary 'jump'.
No way to sugar coat it – this is not good news.
Great summary ~40mins in. https://t.co/4AFKVuwGLw
— Kristian G. Andersen (@K_G_Andersen) January 18, 2021
Great summary ~40mins in.
vote for nobody
January 18, 2021 at 11:54 PM #396017
January 19, 2021 at 12:19 AM #396020jbnwParticipant
- Total Posts: 3,586
if I am interpreting it correctly.
I don’t think that I, or the world economy, would handle another year or so of lockdown well . . .
January 19, 2021 at 12:29 AM #396024retired liberalParticipant
- Total Posts: 3,591
we can go for decades.
We are an arrogant species, believing our fantasy based "facts" are better than the other person's fake facts.
If you are wrong, it will be because you are not cynical enough.
Both major political parties are special interest groups enabling each other for power and money, at the expense of the people they no longer properly serve…
Always wear a proper mask when out and about. The life you save could be both yours and mine.
January 19, 2021 at 12:39 AM #396026
January 19, 2021 at 1:37 AM #396039Bernie BoomerParticipant
- Total Posts: 382
According to “Business Insider: South Africa” the SA variant has been identified in 23 countries as of today – including Canada (so, yeah, it’s probably in the USA, too).
I wish I were more knowledgeable about science – I know I read things (like this WHO discussion of the variants, that says the new UK strain is not phylogenetically related to the older UK strain . . . does that mean it’s a different sort of SARS virus?) that leave me with too many questions and not nearly enough smarts to figure out answers.
I’m with @retired liberal – UBI shouldn’t be a permanent state of play, but it’s desperately needed now, instead of this headlong rush to return everyone to the workplace/school. This is no where close to over.
January 19, 2021 at 6:00 AM #396092
ubi might make some difference but in fact, lots of people still need to go to work, some in dangerous situations, so others can stay home.
ubi would give them some extra cash, but it wouldn’t make them any safer.
and if they didn’t go to work, the rest of us would have to.
January 19, 2021 at 1:52 PM #396168Bernie BoomerParticipant
- Total Posts: 382
Still, there are a lot of people working now that are not in jobs that can only be done in person who might make different economic decisions if they had the financial wherewithal to do so.
I am an MMT proponent, so UBI isn’t my go-to response (I think that a federal jobs guarantee is a better long-term solution) – but in the short-term, it could alleviate a lot. Both suffering, as so many are living with hunger and homelessness (or looming eviction), and a probably small but not insignificant number of people circulating in public on a daily basis out of financial necessity.
There is no rational economic reason not to do it in the short-term. Just a lot of political posturing about “debt” and “tax-payer money.”
I don’t know the answers. I wish I did.
I do know that this is far from over.
January 19, 2021 at 5:27 PM #396252
i don’t know the answers either and also wish i did.
but i sometimes find discussions of people staying home ignore a lot of the people who won’t be able to stay home, some of whom don’t even make minimum wage for their work.
January 19, 2021 at 10:06 PM #396380
Question: What is immune escape?
Answer: Immune escape (aka viral escape and antigen escape) is the ability of a virus to elude an individual’s immune response. In the context of new SARS-CoV-2 strains, the term has come to prominence as scientists examine whether the new strains exhibit immune escape in terms of vaccine resistance. In good news, initial data show that “existing vaccines should work against new coronavirus variants—for now.”
Unlike drug resistance, which is common, vaccine resistance is rare (Figure 1). This paper published in 2017, Why does drug resistance readily evolve but vaccine resistance does not?, offers a useful hypothesis to explain this dichotomy: 1) Vaccines tend to work to prevent disease whereas drugs tend to work to treat disease (i.e. vaccines generally give fewer opportunities for viral replication and spread to others); 2) Vaccines tend to induce immune responses against multiple targets on the virus whereas drugs tend to target very few (i.e. unlike drugs, vaccines generally require immune escape from multiple targets). A more recent paper from these same authors published in November in PLoS Biology describes one more feature of a vaccine that limits resistance: generally, the immune response elicited by the vaccine protects against all circulating types of the virus. What we know of the vaccines we currently have against COVID is that they do meet all three criteria– 1) they prevent disease (though we still don’t know whether they prevent infection); they induce a complex immune response; and 3) they work against all currently circulating variants.
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