We Might Never Get a Good Coronavirus Vaccine
April 21, 2020 at 9:28 AM - Views: 82 #306069
- Total Posts: 795
Hopes for a return to normal life after the coronavirus hinge on the development of a vaccine. But there’s no guarantee, experts say, that a fully effective COVID-19 vaccine is possible.
That may seem counterintuitive. So many brutal viral diseases have been conquered by vaccination — smallpox, polio, mumps, tetanus — that the technique seems all but infallible. But not all viral diseases are equally amenable to vaccination. “Some viruses are very easy to make a vaccine for, and some are very complicated,” says Adolfo García-Sastre, director of the Global Health and Emerging Pathogens Institute at the Icahn School of Medicine at Mount Sinai. “It depends on the specific characteristics of how the virus infects.”
Unfortunately, it seems that COVID-19 is on the difficult end of the scale.
A closely related virus of the same family, SARS, circulated in Asia from late 2002 to mid-2003 and killed more than 700 people. “They really are very similar viruses, both virulent and contagious,” says Rachel Roper, a professor of immunology at East Carolina University who took part in efforts to develop a SARS vaccine.
Given the similarities of the diseases, their response to vaccination would likely be close to identical. So it’s troubling that when researchers conducted animal testing on prospective SARS vaccines, they ran into difficulty. The two versions that they tested both successfully triggered the host animal’s immune system to produce antibodies, but neither was very effective at protecting against the illness. “People think, ‘Oh, if you make antibodies to it, it’s going to be protective,’” says Roper. “That’s not necessarily true. We were able to induce an immune response, but it wasn’t good enough to really protect against the disease.”
It’s possible, Roper fears, that COVID-19 could be a virus that proves resistant to vaccination. “This may be one,” she says. “If we have one, this is going to be it, I think.” The FDA has never approved a vaccine for humans that is effective against any member of the coronavirus family, which includes SARS, MERS, and several that cause the common cold.
Another world health expert says he believes the world will have to figure out a way to live with the coronavirus for “the foreseeable future.”
So what do we do? Do we never travel again? Do sports stadiums never reopen? Does Disney World never reopen? Will cruise ships never sail again? Will we never have school again in classrooms? Will we never have weddings and funerals or graduations? Do sit-down restaurants never reopen? Do museums never re-open? What about gyms, hair salons and barber shops or movie theaters? No more parades? No more birthday or Christmas parties? How long does the economy stay restricted?
Until we find a vaccine?
April 21, 2020 at 11:29 AM #306089
- Total Posts: 1,335
There will be a lot of incentive for science to fine a way, but mother nature bats last. And my guess is she’s pissed.
In America, “Liberty” means “Free to Die in Service of Capital” - Amfortas the hippie
April 21, 2020 at 11:37 AM #306091
- Total Posts: 438
And Karma brought pre-flood JHWH along, as well as Enlil, Demeter, and possibly Nehalennia.
By the way: what if Africa catches the disease and becomes a permanent source of regularly mutated varieties?
April 21, 2020 at 12:04 PM #306095
- Total Posts: 308
C-19 is now. There have been C-19’s in the past. There will be C-19’s in the future. The point is people can’t be so afraid of dying that they refuse to live.
The alternative is reflected in some of the threads I’m reading here where greed, racism, and money is promoted as a reason why people are protesting the stay-at-home directives. It a narrative the media would like you to believe, but it’s not the truth. I tend to not comment on those threads as I enjoy snickering at their unsubstantiated panic instead. Besides, they enjoy believing the lies. There’s several lessons to be learned from their reactions which would be a whole bunch of threads unto themselves. But ultimately, it comes to this: When one demonstrates they’re afraid of their own shadow, then what’s to fear when they say they want to “take the government back by whatever means necessary” or something similar? Truth is, there’s nothing to fear from them, and the opposition knows it.
This is a longer than necessary answer to say that normal people will see that things go back to normal knowing that disease takes some and leaves others, just like it always has. People get cancer; some win and some lose. People get the flu; some win and some lose. You’d like everyone to win, but wishing that changes nothing. And just to be clear, I’m not comparing diseases, I’m just making the case that how much control we exert or try to exert over these things is never the point. It will never be the point.
Some want to hang out in a hidey hole, but many don’t, and over time even fewer will continue to be manipulated to be afraid. People can be controlled by fear. People are being controlled by fear. Seems way too many who wish to continue this isolationism have forgotten that simple truth, using as cover the guise that they care whether people stay alive or not, when the truth is more and more normal humans are willing to be honest about who and what these people really believe yet won’t admit. Because it’s not that they care about people as they claim they do, that’s for damn sure.
April 21, 2020 at 8:26 PM #306171
Mr. Mickeys MomModerator@mrmickeysmom
- Total Posts: 2,951
I’m trying to make sense to your post….” normal people will see that things go back to normal knowing that disease takes some and leaves others, just like it always has.”
The degree of returning to normal, just like it “alway has” cannot even begin to be compared to what it IS. We have not BEEN here before.
You think we’ve been here before and will eventually come out of our “hidey holes” ? What the fuck are you talking about?
Hell, no... I'm not giving up...
April 21, 2020 at 1:01 PM #306105
David the GnomeMember@davidthegnome
- Total Posts: 2,255
Is not a good enough reason to throw caution to the wind. I do not think staying home for a few months is so terrible, not if we can get a temporary UBI passed – which is what we should be demanding.
Say some of you get your way – things open up and people go back to work. Millions wont be able to, have lost their health insurance, jobs, homes, or even their lives. Is a return to this survival of the richest economy really what you want?
A few months should be sufficient time to develop enough testing and perhaps even an effective treatment. While a vaccine might not happen, it also could happen within a year.
If people are forced to go back to work, if distancing measures and restrictions are lifted this early… those who suffer and die will number most highly among the working class and the poor. Have you read the stories of how this is affecting Native Americans and African Americans?
Lack of access to resources is also killing us. It is time to demand a UBI and universal healthcare. I’d be willing to protest, to risk my life for that.
Not for “the economy”. A UBI would negate the need of everyone having to go back to work to avoid starvation and homelessness. So let me ask – in the richest Country on earth – did any of that have to happen at all?
For the first time in many years, there is a chance to stop and take stock. To ask what we are doing wrong. To change the entire fabric of this society.
If we focus on what the many need as opposed to what the few want, we can change the system going forward. If we dont – and it increasingly seems that @floridaprog will have their way…
Then, sure, the lockdown lifts. Hundreds of thousands, perhaps even millions die as those exposed to the virus becomes pretty much everyone. High infection rate, high mortality rate.
You been out to the public places or businesses still open, or in the streets? How many people have you seen that are even wearing protective gear?
We are not ready. The urge of some to get back out there and consequences be damned – is going to cost many, many lives.
I guess being disabled puts me in a rather unique position. I’ve had plenty of those jobs available to us millenials who’s parents couldn’t pay for our education. I’ve spent a decade without health insurance. I’ve worked for less than minimum wage.
I have a rather unique perspective on how ugly shit already was – because I lived through it.
We are on the edge of true disaster. How we deal with this could ultimately set the precedent for how climate change is managed. If the consensus is to do nothing, risk, sacrifice nothing… if that is the precedent set going forward..
Billions will die. Without great change, that is inevitable. Before we get back to business as usual, maybe we should ask ourselves if business as usual is insane.
Or not, whatever.
April 21, 2020 at 7:43 PM #306160
- Total Posts: 795
Mother nature always wins in the end, though. Just like they are saying that within this century, our antibiotics aren’t going to work anymore. There is already resistant-TB spreading through parts of the world as we speak. We create a vaccine for one virus, another will pop up.
Our great grandparents dealt with TB and Spanish Flu.
Our parents grandparents grew up with measles, mumps, and Polio
We’re growing up with HIV, Ebola, SARS, COVID-19, H1N1
Mother nature keeps upping the ante it seems. What will the next generation of viruses look like? There WILL be more. These viruses are mostly zoonotic. That means they have a reservoir within an animal population. As human population grows and our land use expands into forests and vegetation, our interaction with these animals increase. And there is a higher probability that these viruses will mutate and jump species. That’s how a new virus is created. And the fact that our populations are becoming more and more dense, the virus can spread easily. Why do you think NYC has a worse outbreak than anywhere else? Because people are living on top of each other.
The core of the problem is not lack of nationalized healthcare funding. The problem is what no one wants to talk about…..overpopulation.
April 21, 2020 at 2:09 PM #306111
- Total Posts: 2,775
Rolling Stones, Ac/Dc, Rush, The Guess Who (actually the real lineup, for once) and (for Hell knows what reason) Justin Timberlake?? Well.. a MOSTLY great show anyway…..
Yes those are washing machines on stage. Probably not enough to do laundry for that crowd though.
500,000 people in one place? Yeah, that’s not happening again any time soon. Or any concert tours at all, for that matter….
"Those who make peaceful revolution impossible will make violent revolution inevitable". - John F. Kennedy
April 21, 2020 at 8:02 PM #306163
Mr. Mickeys MomModerator@mrmickeysmom
- Total Posts: 2,951
… including seeing Neil Pert in this number. I know this phase of my life has come and gone, but it re-calibrated a morning full of news that was frankly making my heart hurt.
Hell, no... I'm not giving up...
April 21, 2020 at 9:19 PM #306186
- Total Posts: 1,181
So, we “may” have a vaccine by the fall or we “might” never get one. Quite the range of possibilities. It’s almost as if we have no idea what’s going to happen and all of these prognostications are useless, nothing but hot air, gaggles of scientists and MDs jerking themselves off and sniffing their own farts. The only thing interesting about this bullshit is how anyone can push whatever narrative they want because they can always find an expert of some sort who says what they want to hear.
April 21, 2020 at 9:26 PM #306187
April 21, 2020 at 10:43 PM #306222
- Total Posts: 2,866
… corporate “get back to work” cheerleaders aren’t practicing what they preach.
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